Peptic ulcer occurs in that pat of gastrointesinal tract which is exposed to gastric acid and a protein digesting enzyme called pepsin.
IT DEVELOPS DUE TO IMBALANCE BETWEEN THE AGRESSIVE AND DEFENSIVE FACTORS DAMAGED.
THE AGGRESSIVE FACTORS INCLUDE
1.HYDROCHLORIC ACID: the ph of HCl in our stomach is extremely low ie 2-3, that means it is highly acidic and damaging, to the lining of the stomach and small intestine.
2.PEPSIN:
A PROTEIN DIGESTING ENZYME STARTS DIGESTING INTESTINAL WALL IF THE PROTECTIVE COVER IS DAMAGED CAUSING ULCERS.
3. SMOKING
smoking plays a havoc in development of peptic ulcers
4.CHRONIC STRESS
people who are chronically stressed are commonly affected with this disease.
5.Obesity
obesity causes the reflux of food back from small intestine to stomach,therefore exposing to more acid
6.Alcohol consumption
7.regular intake of spicy foods
8.HELICOBACTER PYLORI INFECTION
Now considered to be the most notorius and important factor in the development of peptic ulcer. Helicobacter pylori is commonly found in the stomach lining of patients suffering from chronic ulcers.
Its eradication from the intestine is etremely difficult and involves the intake of 3-4 antibiotics and PPIs i.e.antiacidity medicine.
DEFENSIVE CAUSES
GASTRIC MUCOSA; gastric ulcer mucosa is caused derceased gastric mucus formation due to prostaglandins.
DECREASED RESISTANCE TO BACTERIA ,BODYS IMMUNITY ALSO PLAYS A GOOD PART IN APLLICATION DUE TO DECREASED R ESISTANCE.
O,BLOOD GROUP IS COMMONLY KNOWN TO BE ASSOCIATED WITH GASTRIC ULCERS
IT DEVELOPS DUE TO IMBALANCE BETWEEN THE AGRESSIVE AND DEFENSIVE FACTORS DAMAGED.
THE AGGRESSIVE FACTORS INCLUDE
1.HYDROCHLORIC ACID: the ph of HCl in our stomach is extremely low ie 2-3, that means it is highly acidic and damaging, to the lining of the stomach and small intestine.
2.PEPSIN:
A PROTEIN DIGESTING ENZYME STARTS DIGESTING INTESTINAL WALL IF THE PROTECTIVE COVER IS DAMAGED CAUSING ULCERS.
3. SMOKING
smoking plays a havoc in development of peptic ulcers
4.CHRONIC STRESS
people who are chronically stressed are commonly affected with this disease.
5.Obesity
obesity causes the reflux of food back from small intestine to stomach,therefore exposing to more acid
6.Alcohol consumption
7.regular intake of spicy foods
8.HELICOBACTER PYLORI INFECTION
Now considered to be the most notorius and important factor in the development of peptic ulcer. Helicobacter pylori is commonly found in the stomach lining of patients suffering from chronic ulcers.
Its eradication from the intestine is etremely difficult and involves the intake of 3-4 antibiotics and PPIs i.e.antiacidity medicine.
DEFENSIVE CAUSES
GASTRIC MUCOSA; gastric ulcer mucosa is caused derceased gastric mucus formation due to prostaglandins.
DECREASED RESISTANCE TO BACTERIA ,BODYS IMMUNITY ALSO PLAYS A GOOD PART IN APLLICATION DUE TO DECREASED R ESISTANCE.
O,BLOOD GROUP IS COMMONLY KNOWN TO BE ASSOCIATED WITH GASTRIC ULCERS
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