ANTIBIOTICS
TOPICAL: erythromycin or clindamycin, NADIFLOXACIN gel applied to the skin after washing the face from mild antibacterial soap.Apply before sleeping at night for its good effect.
ORAL: Oxytetracycline taken on empty stomach without food in a dose upto 1.5 grams daily in a day in two divided doses.
BENZOYL PEROXIDE 0.5 AND 1% GEL
It is the cornerstone in the treatment of acne. It kills the bacteria by releasing oxidants which kill and decrease the baterial population. It also a keratolytic which helps in removing the dead cells and opening the pores.Its dries the oil in the follicles which indirectly decreases bacterial population. due to its multimodality of action its the most peferred teatment in the acne.
Dosage: a small quantity should be applied after washing face by a mild soap. keep the cream for 20-30 minutes and wash off. Initially it will give a tingling and burning sensation but it goes off soon. Should be avoided if severe rashes occur on the face.
WOMENS SPECIFIC TREATMENT
Oral contraceptive pills and anti androgens like cyproterone acetate are very effective and given to only women.
Adapalene Topical Gel
Its acts on retinoind receptos and promotes follicular diffrentiation. it has very good anti inflammatory effects.
ISOTRETINOIN
THIS IS THE MEDICINE THAT REVOLUTIONISED THE TREATMENT OF ACNE.
SEVERE OR MODERATE UNRESPONSIVE TO TRADITIONAL TREARMENT IS TAKEN IN THE DOSE OF 0-5 TO 1 MG/KG.
MECHANISM OF ACTION: IT A GOLD STANDARD FOR DECREASING OIL PRODUCTION.
IT ALSO PROMOTES KERAEATINISATOION.IT CAUSES DRY SKIN . BECAUSE OF ITS OIL DECREASING EFFECT THE OIL GLAND GETS DRIED UP INDIECTLY DECREASE THE BACTERIAL POPULATION
A TREATMENT COURSE OF ATLEST 14 MONTHS IS REQUIRED.
IT IS STRICTLY PROHIBITED IN PREGNANT WOMEN BECAUSE OF ITS SIDE EFFECT OF TERATOGENICITY CAUSE BIRTH DEFECTS IN NEW BORNS
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